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In Vivo Imaging

 

The In Vivo Department focuses its activities on multimodal preclinical imaging, including isotopic techniques (PET, SPECT, and autoradiography), X-ray imaging (µCT), magnetic resonance imaging (MRI 9.4T and 1T), optical imaging (BLI, FLI, and CLI), and photoacoustic imaging (MSOT).

The department supports both industrial and academic partners by developingtailor-made experimental protocols for image acquisition and analysis. These customized approaches are designed to address scientific questions at morphological, functional, and molecular levels using small animal models.

Its research activities cover a broad range of application fields, including oncology, inflammation, drugs biodistribution, skeletal disorders, cell tracking (stem cells, parasites, …), and infectiology, angiology (angiography, hypoxia, …).

The facility is equipped with state-of-the-art technology and includes a dedicated animal housing unit directly connected to the imaging suites, ensuring optimal experimental workflow and compliance with preclinical research standards.


Nuclear Molecular Imaging & CT    Non-Ionising Molecular Imaging

Nuclear Molecular Imaging & CT


Services


  • Integrated animal facility
  • Animal models (implementation & development)
  • Design and manufacturing of contrast agent & radiotracers
  • Radiolabeling service
  • Multimodal imaging registration & processing


Equipments


  • High resolution µCT
    Bruker, Skyscan 1276
  • PET/CT
    nanoScan PETCT, Mediso
  • Gamma camera
    VECTor platform, MILabs-Rigaku


DOUMONT Gilles, PhD

Facilty Manager

Publications

LEVILLAIN Hugo, Pr

Academic Supervisor

FLAMEN Patrick

Supporting Unit

PASSON Nicolas

PET/SPECT/CT imaging technician

Publications

VAN HEYMBEEK Christophe

In vivo technician

DE MAESENEIRE Coraline

Research Logistician

Publications

Non-Ionising Molecular Imaging 


Services


  • Integrated animal facility
  • Animal models (implementation & development)
  • Design and manufacturing of contrast agent & fluorescent dyes
  • Luciferase expressing cells
  • Multimodal imaging regsitration & processing


Equipments


  • 9.4T MRI
    Bruker, Biospec 94/20, equipped with mouse head & body, rat body & surface 1H coils, 19F/1H mouse body coil, 13C/1H surface coil.
  • 1T MRI
    Bruker, ICON, equipped with mouse head & body 1H coils.
  • MSOT-UCT
    iThera Medical, inVision Echo for simultaneous optoacoustic and ultrasound tomography, equipped with internal mouse and small rat holders, and 3D Cup hand-held detector.
  • Optical Imaging
    Biospace Lab, PhotonImager Optima for simultaneous imaging of up to 10 mice and imaging of other small animals such as rats, eels, zebrafishes, … Multimodal system designed for bioluminescence, fluorescence and Cherenkov luminescence imaging, and also equipped with additional 4-Views, MACROLENS and X-Rays modules.
  • Near-infrared fluorescence imaging
    KearLabs, KIS750) with free access to the animal during real-time imaging.

LARBANOIX Lionel, PhD

Facility Manager

Publications

LAURENT Sophie, Pr

Academic supervisor

Publications

BOUTRY Sébastien, PhD

Researcher

Publications

 

VAN HEYMBEEK Christophe

In Vivo Technician